How ANDEMBRY Works

Groundbreaking
HAE Treatment

ANDEMBRY is the first and only approved prophylaxis treatment for HAE patients proven to work differently from other options by inhibiting Factor XIIa at the top of the HAE pathway.

How ANDEMBRY Works

  • Inhibits the HAE cascade at the top to prevent HAE attacks
  • Factor XII is the first protein activated in the contact activation pathway
  • Factor XIIa plays a key role in an HAE attack by converting prekallikrein to kallikrein when C1-esterase inhibitor (C1INH) is missing or dysfunctional

HMWK = high-molecular weight kininogen

Your Journey, Without Interruptions

ANDEMBRY is a powerful prophylaxis treatment with a noticeable reduction in HAE attacks beginning at Week 1.

Photo does not depict actual patient

Photo does not depict actual patient

Your Journey, Without Interruptions

ANDEMBRY is a powerful prophylaxis treatment with a noticeable reduction in HAE attacks beginning at Week 1.

Resources

Downloadable resources that can provide additional information about ANDEMBRY

personalized support

One-on-one support throughout your ANDEMBRY journey

Simple dosing

Once-monthly dosing from Day 1 
for all patients 12 years and older

Safety Information

Important Safety Information